Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.41 |
| ▸ | CDC25B | P30305 | 7/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948297 | 0.91 | GJB2 (0.44) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6949834 | 0.89 | GJB2 (0.46) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6949828 | 0.89 | GJB2 (0.46) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7582817 | 0.87 | NT5E (0.44) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7079491 | 0.82 | PTPN1 (0.51) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL7079489 | 0.82 | PTPN1 (0.51) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL7571873 | 0.82 | SSTR1 (0.53) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7571875 | 0.82 | SSTR1 (0.53) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14363518 | 0.82 | NT5E (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14088876 | 0.82 | NT5E (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534481-B1 | Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin | SANOFI-SYNTHELABO (FR) | 2003-03-18 | — | — | US | disclosed |