Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949834 | 1.00 | GJB2 (0.46) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL7582813 | 0.92 | LGALS8 (0.42) | GJB2NT5EPTPN1CDC25BSSTR4 | |
| SCHEMBL6948297 | 0.89 | GJB2 (0.44) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL6948295 | 0.89 | GJB2 (0.44) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL7582817 | 0.88 | NT5E (0.44) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL22677442 | 0.86 | SSTR1 (0.49) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL22677766 | 0.86 | SSTR1 (0.51) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL22678393 | 0.86 | SSTR1 (0.51) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL22678413 | 0.85 | SSTR1 (0.51) | GJB2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL22677685 | 0.84 | SSTR1 (0.51) | GJB2NT5EPTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534481-B1 | Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin | SANOFI-SYNTHELABO (FR) | 2003-03-18 | — | — | US | disclosed |
| EP-0912613-B1 | SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |