Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.42 |
| ▸ | CDC25B | P30305 | 6/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582813 | 0.91 | LGALS8 (0.42) | NT5ECYP2D6ALDH1A1MAPK1GJB2 | |
| SCHEMBL7079491 | 0.91 | PTPN1 (0.51) | NT5ECYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL7079489 | 0.91 | PTPN1 (0.51) | NT5ECYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL6949828 | 0.88 | GJB2 (0.46) | NT5ECYP2D6GJB2PTPN1CDC25B | |
| SCHEMBL6949834 | 0.88 | GJB2 (0.46) | NT5ECYP2D6GJB2PTPN1CDC25B | |
| SCHEMBL6948295 | 0.87 | GJB2 (0.44) | NT5EGJB2PTPN1CDC25BSSTR1 | |
| SCHEMBL7571875 | 0.87 | SSTR1 (0.53) | NT5EGJB2PTPN1CDC25BSSTR1 | |
| SCHEMBL7571873 | 0.87 | SSTR1 (0.53) | NT5EGJB2PTPN1CDC25BSSTR1 | |
| SCHEMBL6553277 | 0.86 | CYP2D6 (0.46) | NT5ECYP2D6ALDH1A1MAPK1PTPN1 | |
| SCHEMBL6553285 | 0.86 | CYP2D6 (0.46) | NT5ECYP2D6ALDH1A1MAPK1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912613-B1 | SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |