Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952749 | 0.89 | KDM4E (0.45) | KDM4EKDM3BALDH1A1HSD17B10HPGD | |
| SCHEMBL1663484 | 0.89 | PTK2 (0.46) | KDM4EKDM3BALDH1A1HSD17B10HPGD | |
| SCHEMBL3429404 | 0.79 | PTK2 (0.44) | KDM4EKDM3BALDH1A1HSD17B10HPGD | |
| SCHEMBL6778119 | 0.75 | KDM4E (0.35) | KDM4EKDM3BALDH1A1HSD17B10HPGD | |
| SCHEMBL6767802 | 0.74 | ALPL (0.39) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL7394232 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10HPGDDYRK1A | |
| SCHEMBL7385629 | 0.73 | ROCK2 (0.47) | KDM4EKDM3BALDH1A1HSD17B10HPGD | |
| SCHEMBL7381669 | 0.70 | HTT (0.34) | KDM4EKDM3BHSD17B10HPGDKMT2A | |
| SCHEMBL6304807 | 0.69 | TSHR (0.52) | ALDH1A1PTK2 | |
| SCHEMBL28986056 | 0.69 | KDM4E (0.39) | KDM4EKDM3BALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6262272-B1 | REACTING FURAN CARBOXYLIC ACID DERIVATIVE WITH ACID CHLORIDE OR ACID ANHYDRIDE IN INERT SOLVENT CONTAINING ACID RECEPTOR; ADDING AROMATIC AMINE COMPOUND TO FORM PYRROLE CARBOXAMIDE COMPOUND | PFIZER INC | 2001-07-17 | — | — | US | disclosed |
| EP-1030838-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999025684-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PRODUCTS INC. (US) | 1999-05-27 | — | — | WO | disclosed |