Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684123 | 0.85 | TDP1 (0.43) | CYP3A4TDP1ALDH1A1TSHRMAPK1 | |
| SCHEMBL14881372 | 0.84 | TDP1 (0.38) | CYP3A4TDP1ALDH1A1TSHRTP53 | |
| SCHEMBL3150471 | 0.80 | ESR1 (0.35) | CYP3A4TDP1ALDH1A1TSHRESR1 | |
| SCHEMBL5993333 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20929091 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1TSHRMAPK1 | |
| SCHEMBL29353640 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1TSHRMAPK1 | |
| SCHEMBL7716869 | 0.78 | GABRA1 (0.34) | CYP3A4ALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL20855267 | 0.77 | NPC1 (0.35) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10241971 | 0.77 | TP53 (0.43) | CYP3A4TDP1ALDH1A1MAPK1TP53 | |
| SCHEMBL20915694 | 0.77 | CYP1A2 (0.36) | CYP3A4ALDH1A1TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890327-B2 | Phosphorescent transition metal complex, its preparation and use | CITY UNIVERSITY OF HONG KONG (HK) | 2018-02-13 | — | — | US | disclosed |
| US-20170114275-A1 | PHOSPHORESCENT TRANSITION METAL COMPLEX, ITS PREPARATION AND USE | CITY UNIVERSITY OF HONG KONG (HK) | 2017-04-27 | — | — | US | disclosed |
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1202724-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1150950-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001005393-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |
| WO-2000041505-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114275-A1 | PHOSPHORESCENT TRANSITION METAL COMPLEX, ITS PREPARATION AND USE | DNAJA3, HSPE1, MDH2 | CYP3A4 3471/4885TDP1 2894/4885ALDH1A1 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.