Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365308 | 0.85 | GAA (0.49) | NPC1RAB9AMDM2SMN1; SMN2 | |
| SCHEMBL8026110 | 0.76 | MTNR1A (0.45) | CYP1A2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6949404 | 0.76 | MTNR1A (0.45) | CYP1A2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6958621 | 0.75 | CYP1A2 (0.56) | CYP1A2HSD17B10NPC1RAB9AALPI | |
| SCHEMBL2397070 | 0.75 | CYP1A2 (0.61) | CYP1A2HSD17B10ALPIPKMPTGS1 | |
| SCHEMBL7483692 | 0.75 | CYP1A2 (0.61) | CYP1A2HSD17B10ALPIPKMPTGS1 | |
| SCHEMBL1566396 | 0.75 | CYP1A2 (0.61) | CYP1A2HSD17B10ALPIPKMPTGS1 | |
| SCHEMBL8507342 | 0.75 | KEAP1 (0.59) | CYP1A2ALDH1A1MAPK1MAPTALPI | |
| SCHEMBL1897012 | 0.74 | CPA1 (0.45) | CYP1A2MMEACEALDH1A1HPGD | |
| SCHEMBL6054519 | 0.74 | CYP1A2 (0.54) | CYP1A2ALDH1A1HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| EP-0154904-A1 | Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines | E.R. Squibb & Sons, Inc. (US) | 1985-09-18 | — | — | EP | disclosed |
| EP-0142335-A2 | Lactam containing compounds | E.R. Squibb & Sons, Inc. (US) | 1985-05-22 | — | — | EP | disclosed |