Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | SGK1 | O00141 | 1/20 | 0.55 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698578 | 0.85 | NR4A2 (0.58) | NR4A2IMPDH2MAPK1HSD17B10SGK1 | |
| SCHEMBL28377762 | 0.84 | NR4A2 (0.81) | NR4A2IMPDH2MAPK1HSD17B10ASH1L | |
| SCHEMBL29221047 | 0.83 | PTPN1 (0.62) | CAMKK2NR4A2IMPDH2AXLSGK1 | |
| SCHEMBL22044149 | 0.82 | PTPN1 (0.59) | NR4A2AXL | |
| SCHEMBL5424839 | 0.82 | PTPN1 (0.61) | BRD4GPR84ASH1LGAACASP3 | |
| SCHEMBL29221014 | 0.82 | PTPN1 (0.61) | CAMKK2AXLSGK1ASH1L | |
| SCHEMBL179165 | 0.82 | PTPN1 (0.61) | CAMKK2IMPDH2AXLSGK1ASH1L | |
| SCHEMBL5429419 | 0.82 | PTPN1 (0.61) | BRD4GPR84ASH1LGAACASP3 | |
| SCHEMBL28416622 | 0.82 | NR4A2 (0.78) | NR4A2IMPDH2MAPK1HSD17B10ASH1L | |
| 3-Phenylindole SCHEMBL84056 | 0.82 | IMPDH2 (0.71) | NR4A2IMPDH2MAPK1HSD17B10ASH1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC | 2025-06-05 | — | — | US | disclosed |
| CN-113631548-B | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-3947360-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | Zoetis Services LLC (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020198478-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2020-10-01 | — | — | WO | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | HTR2B, HTR1B, HTR5A | CAMKK2 2465/4885NR4A2 1632/4885IMPDH2 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.