Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 4/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462898 | 0.73 | RIPK1 (0.40) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL872854 | 0.71 | CYP2C19 (0.46) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL6681496 | 0.70 | TAAR1 (0.50) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL4137948 | 0.69 | GRIN1 (0.36) | CYP2D6ALDH1A1CYP2C19HSD17B10MAPK1 | |
| SCHEMBL12356880 | 0.68 | ALDH1A1 (0.41) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL907893 | 0.68 | CYP2D6 (0.39) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL6230799 | 0.67 | ALDH1A1 (0.39) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL17965831 | 0.67 | CYP2D6 (0.35) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 | |
| SCHEMBL27278714 | 0.66 | KCNN4 (0.43) | ALDH1A1CYP2C19MAPK1KIF11 | |
| SCHEMBL3997340 | 0.64 | ALDH1A1 (0.49) | CYP2D6ALDH1A1CYP2C19HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |