Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116137 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL693978 | 0.90 | MEN1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL693294 | 0.89 | MEN1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL694017 | 0.88 | FAAH (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL694155 | 0.87 | CNR1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL693478 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL694099 | 0.86 | CNR1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL15197208 | 0.86 | KMT2A (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL3103378 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL3108889 | 0.86 | ENPP2 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421829-A2 | 2,5-DISUBSTITUTED ARYLSULFONAMIDE CCR3 ANTAGONISTS | Axikin Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123956-A2 | 2,5-DISUBSTITUTED ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | WO | disclosed |