Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216090 | 0.91 | — | — | |
| SCHEMBL20503228 | 0.87 | PPARG (0.34) | — | |
| SCHEMBL4101948 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1989127 | 0.81 | — | — | |
| SCHEMBL498489 | 0.77 | — | — | |
| SCHEMBL29265338 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL5227293 | 0.73 | — | — | |
| SCHEMBL20740669 | 0.72 | DHFR (0.43) | — | |
| SCHEMBL1508735 | 0.69 | — | — | |
| Phenylacetaldehyde SCHEMBL6378611 | 0.69 | CYP3A4 (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |