SCHEMBL6948878

SCHEMBL6948878

Cc1cc(C)c2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)NCCCCNC(=O)c4ccc(C=NN)cc4)c3Cl)c2n1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 3/20 0.82
RORC P51449 17/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950086 0.99 BDKRB2 (0.81) BDKRB2RORC
SCHEMBL8045430 0.99 BDKRB2 (0.82) BDKRB2RORC
Hydrochloric Acid SCHEMBL8040364 0.99 BDKRB2 (0.80) BDKRB2RORC
SCHEMBL6945418 0.99 BDKRB2 (0.84) BDKRB2RORC
Hydrochloric Acid SCHEMBL8045266 0.98 BDKRB2 (0.83) BDKRB2RORC
SCHEMBL6953309 0.98 BDKRB2 (0.80) BDKRB2RORC
Hydrochloric Acid SCHEMBL8041915 0.97 BDKRB2 (0.79) BDKRB2RORC
SCHEMBL6947379 0.94 BDKRB2 (0.79) BDKRB2RORC
SCHEMBL8042006 0.93 BDKRB2 (0.74) BDKRB2RORC
SCHEMBL8040397 0.93 BDKRB2 (0.75) BDKRB2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944618-B1 NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE FOURNIER IND & SANTE (FR) 2003-09-24 EP disclosed