Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040397 | 0.99 | BDKRB2 (0.75) | BDKRB2RORC | |
| SCHEMBL8045430 | 0.94 | BDKRB2 (0.82) | BDKRB2RORC | |
| SCHEMBL6945418 | 0.93 | BDKRB2 (0.84) | BDKRB2RORC | |
| SCHEMBL6948878 | 0.93 | BDKRB2 (0.82) | BDKRB2RORC | |
| Hydrochloric Acid SCHEMBL8045266 | 0.92 | BDKRB2 (0.83) | BDKRB2RORC | |
| SCHEMBL6950086 | 0.92 | BDKRB2 (0.81) | BDKRB2RORC | |
| Hydrochloric Acid SCHEMBL8040364 | 0.92 | BDKRB2 (0.80) | BDKRB2RORC | |
| SCHEMBL6947379 | 0.91 | BDKRB2 (0.79) | BDKRB2RORC | |
| SCHEMBL6953309 | 0.90 | BDKRB2 (0.80) | BDKRB2RORC | |
| SCHEMBL8041999 | 0.90 | BDKRB2 (0.87) | BDKRB2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063791-A | N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-05-16 | — | — | US | disclosed |