Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274700 | 0.86 | ATM (0.58) | MEN1KMT2ATAAR1EPHX1TSHR | |
| SCHEMBL3499885 | 0.86 | ATM (0.58) | MEN1KMT2ATAAR1EPHX1TSHR | |
| SCHEMBL27925079 | 0.86 | ATM (0.58) | MEN1KMT2ATAAR1EPHX1TSHR | |
| SCHEMBL6952487 | 0.84 | MEN1 (0.54) | MEN1KMT2ATAAR1EPHX1DAGLA | |
| SCHEMBL7882117 | 0.84 | MMP8 (0.55) | MEN1KMT2ATAAR1EPHX1DAGLA | |
| SCHEMBL6952367 | 0.84 | MMP8 (0.55) | MEN1KMT2ATAAR1EPHX1DAGLA | |
| SCHEMBL25100758 | 0.83 | TSHR (0.51) | TAAR1TSHRALDH1A1THRBCYP2C9 | |
| SCHEMBL6803690 | 0.83 | TSHR (0.51) | TAAR1TSHRALDH1A1THRBCYP2C9 | |
| SCHEMBL27556826 | 0.83 | TSHR (0.51) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL9440084 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2ATAAR1DAGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |