Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604266 | 0.78 | PTK2 (0.51) | KDM4EALDH1A1POLBEGFRCSF1R | |
| Hydrochloric Acid SCHEMBL5758288 | 0.76 | GRIN2D (0.43) | KDM4EALDH1A1POLBEGFRCSF1R | |
| SCHEMBL5756449 | 0.72 | MAPT (0.49) | ALDH1A1MAPK1HPGDKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5755808 | 0.68 | CA1 (0.44) | ALDH1A1EGFRCSF1RMAPK1S1PR2 | |
| SCHEMBL22049279 | 0.65 | MEN1 (0.59) | KDM4EALDH1A1POLBMAPK1HPGD | |
| SCHEMBL27586486 | 0.65 | MAOB (0.41) | MAOAMAOBSLC6A4DRD1DRD4 | |
| SCHEMBL5247296 | 0.63 | PDE10A (0.44) | EGFRCSF1RPDE10AADRA1DADRA1A | |
| SCHEMBL5755108 | 0.63 | MAPT (0.54) | ALDH1A1MAPK1DRD1KMT2AMEN1 | |
| SCHEMBL38095 | 0.63 | IDH1 (0.35) | — | |
| SCHEMBL12288774 | 0.63 | LMNA (0.41) | KDM4EALDH1A1MAPK1S1PR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349535-A2 | INDOLE/INDOLINE BASED HYBRID DYES AND INDOLE/INDOLINE BASED HYBRID DYE INTERMEDIATE PRODUCTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055609-A2 | INDOLE/INDOLINE BASED HYBRID DYES AND INDOLE/INDOLINE BASED HYBRID DYE INTERMEDIATE PRODUCTS | HENKEL KGAA (DE) | 2002-07-18 | — | — | WO | disclosed |