Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904036 | 0.84 | CES2 (0.44) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL10887048 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX15CES2CES1LMNA | |
| SCHEMBL10895833 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX15CES2CES1LMNA | |
| SCHEMBL2109549 | 0.82 | ALDH1A1 (0.58) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL11033724 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL28184973 | 0.81 | TSHR (0.44) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL11552705 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL10616138 | 0.80 | KDM4E (0.50) | ALDH1A1CES2CES1POLBLMNA | |
| SCHEMBL9657789 | 0.80 | ALDH1A1 (0.48) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL2154401 | 0.80 | ALDH1A1 (0.48) | ALDH1A1ALOX15CES2CES1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400052-B | Synthesis method of methyl o-, m-and p-trifluoromethylbenzoate | 淄博飞源化工有限公司 | 2020-05-01 | — | — | CN | claimed |
| CN-101516836-B | Process for preparing a sulphonic acid anhydride | RHODIA OPERATIONS | 2013-09-04 | — | — | CN | claimed |
| CN-101516836-A | Process for preparing a sulphonic acid anhydride | RHODIA OPERATIONS (FR) | 2009-08-26 | — | — | CN | claimed |
| CN-1216028-C | Preparation method of 3,5-di (trifluoromethyl) benzoyl chloride and new 3,5-di(triahlo) benzoylate A and 3,5-dimethyl benzoylate A | BAYER AG (DE) | 2005-08-24 | — | — | CN | claimed |
| CN-1308050-A | Preparation method of 3,5-di (trifluoromethyl) benzoyl chloride and new 3,5-di(triahlo) benzoylate A and 3,5-dimethyl benzoylate A | BAYER AG (DE) | 2001-08-15 | — | — | CN | claimed |
| US-4500471-A | REACTING TRICHLORO-OR TRIBROMOMETHYLBENZOYL HALIDES WITH HYDROGEN FLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-02-19 | — | — | US | claimed |
| EP-0038223-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0018481-B1 | PROCESS FOR PRODUCING ALPHA, ALPHA, ALPHA-TRIFLUORO-O-TOLUIC FLUORIDE | NIHON NOHYAKU CO., LTD. (JP) | 1983-01-12 | — | — | EP | claimed |
| EP-0015577-B1 | PROCESS FOR PRODUCING 1,1,3,3-TETRAFLUORO-1,3-DIHYDRO-ISOBENZOFURAN | NIHON NOHYAKU CO., LTD. (JP) | 1982-02-03 | — | — | EP | claimed |
| US-4305889-A | Process for producing α, α, α-trifluoro-o-toluic fluoride | NIHON NOHYAKU CO., LTD. (JP) | 1981-12-15 | — | — | US | claimed |
| EP-0038223-A1 | Process for the preparation of trifluoromethylbenzoyl halides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-10-21 | — | — | EP | claimed |
| US-4283344-A | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| EP-0018481-A1 | Process for producing alpha, alpha, alpha-trifluoro-o-toluic fluoride | NIHON NOHYAKU CO., LTD. (JP) | 1980-11-12 | — | — | EP | claimed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | claimed |
| JP-55129243-A | — | — | None | — | — | JP | disclosed |
| JP-55129278-A | — | — | None | — | — | JP | disclosed |
| JP-56103138-A | — | — | None | — | — | JP | disclosed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |
| US-3966832-A | Continuous process for preparing derivatives of benzene with fluorinated side chains from the corresponding chlorine compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |