SCHEMBL3904036

SCHEMBL3904036

O=C(c1ccccc1C(Cl)(Cl)Cl)c1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ALDH1A1 P00352 5/20 0.43
CNR2 P34972 2/20 0.42
ALOX15 P16050 3/20 0.40
GAA P10253 2/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RECQL P46063 1/20 0.40
LMNA P02545 2/20 0.39
MAPK14 Q16539 1/20 0.38
ELANE P08246 1/20 0.38
CYP1A2 P05177 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
AKR1C3 P42330 1/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10892063 0.87 AKR1C3 (0.55) ALDH1A1GAAMAPTLMNAELANE
SCHEMBL6949321 0.84 ALDH1A1 (0.50) CES2CES1ALDH1A1CNR2ALOX15
SCHEMBL2109549 0.84 ALDH1A1 (0.58) CES2CES1ALDH1A1ALOX15TSHR
SCHEMBL10616138 0.82 KDM4E (0.50) CES2CES1ALDH1A1GAATSHR
SCHEMBL6755625 0.82 ELANE (0.44) CES2CES1ALDH1A1CNR2ALOX15
SCHEMBL10971984 0.79 CES2 (0.39) CES2CES1ALDH1A1CNR2ALOX15
SCHEMBL3915309 0.78 ALDH1A1 (0.42) CES2CES1ALDH1A1CNR2ALOX15
SCHEMBL11760095 0.77 PLK1 (0.45) ALDH1A1ALOX15TSHRMAPTSMN1; SMN2
SCHEMBL11640332 0.77 TSHR (0.55) ALDH1A1ALOX15TSHRPOLBMAPT
SCHEMBL27325599 0.77 PDK2 (0.41) CES2CES1ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7574959-B2 Radiation-sensitive compositions and imageable elements based thereon KODAK GRAPHIC COMMUNICATIONS, GMBH (DE) 2009-08-18 US disclosed
US-20070142490-A1 Radiation-sensitive compositions and imageable elements based thereon BAUMANN HARALD 2007-06-21 US disclosed
EP-1690138-A1 RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE ELEMENTS BASED THEREON Kodak Polychrome Graphics GmbH (DE) 2006-08-16 EP disclosed
WO-2005054952-A1 RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE ELEMENTS BASED THEREON KODAK POLYCHROME GRAPHICS GMBH (DE) 2005-06-16 WO disclosed
WO-1999023197-A1 PROCESSES OF SOAKING FABRICS WITH A LIQUID AQUEOUS PERSULFATE SALT-CONTAINING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1999-05-14 WO disclosed
WO-1999023196-A1 LIQUID AQUEOUS BLEACHING COMPOSITIONS PACKAGED IN A UV RESISTANT CONTAINER THE PROCTER & GAMBLE COMPANY (US) 1999-05-14 WO disclosed
WO-1999023294-A1 PROCESSES OF BLEACHING FABRICS THE PROCTER & GAMBLE COMPANY (US) 1999-05-14 WO disclosed
WO-1999023195-A1 MULTI-PURPOSE LIQUID AQUEOUS BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-05-14 WO disclosed
EP-0915150-A1 Processes of soaking fabrics with a liquid aqueous persulfate salt-containing composition THE PROCTER & GAMBLE COMPANY (US) 1999-05-12 EP disclosed
EP-0913463-A1 Multi-purpose liquid aqueous bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1999-05-06 EP disclosed
EP-0913515-A1 Process of bleaching fabrics THE PROCTER & GAMBLE COMPANY (US) 1999-05-06 EP disclosed
EP-0913462-A1 Liquid aqueous bleaching compositions packaged in a UV-resistant container THE PROCTER & GAMBLE COMPANY (US) 1999-05-06 EP disclosed
EP-0081323-A1 Curable ink or paint containing electrically conductive metal particles JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1983-06-15 EP disclosed