Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389003 | 0.82 | FAAH (0.53) | GPR119KDM4EPKMFAAHKEAP1 | |
| SCHEMBL13989309 | 0.79 | GPR119 (0.47) | GPR119KDM4EPKMFAAHSLC2A1 | |
| SCHEMBL27035706 | 0.78 | GPR119 (0.53) | GPR119KDM4EPKMFAAHSLC2A1 | |
| SCHEMBL3865846 | 0.76 | GPR119 (0.50) | GPR119KDM4EPKMFAAHKEAP1 | |
| SCHEMBL5267591 | 0.76 | FAAH (0.49) | GPR119KDM4EPKMFAAHNPC1 | |
| SCHEMBL389652 | 0.76 | FAAH (0.55) | GPR119KDM4EPKMFAAHSLC2A1 | |
| SCHEMBL390114 | 0.76 | GPR119 (0.47) | GPR119KDM4EPKMFAAHSLC2A1 | |
| SCHEMBL4242463 | 0.76 | GPR119 (0.53) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL389218 | 0.75 | GPR119 (0.54) | GPR119KDM4EPKMFAAHSLC2A1 | |
| SCHEMBL388825 | 0.74 | KDM4E (0.46) | GPR119KDM4EPKMFAAHSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |