Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953811 | 0.90 | CHRM2 (0.54) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL6942774 | 0.84 | SIGMAR1 (0.58) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL6952267 | 0.82 | CHRM2 (0.65) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL13003260 | 0.80 | SIGMAR1 (0.68) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL3996386 | 0.78 | CHRM2 (0.63) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL17294676 | 0.78 | CHRM3 (0.72) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL3996281 | 0.76 | CHRM2 (0.66) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL27701873 | 0.76 | CHRM2 (0.57) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL3997077 | 0.76 | SIGMAR1 (0.61) | CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL10361893 | 0.76 | SIGMAR1 (0.65) | KMT2ASIGMAR1CYP2D6CYP2C9DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11193271-A | — | — | None | — | — | JP | disclosed |
| EP-0913393-B1 | Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it | SSP CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6060485-A | UROGENITAL DISORDERS | SSP CO., LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| JP-H11193271-A | ARYLACETAMIDE DERIVATIVE OR ITS SALT AND MEDICINE CONTAINING THE SAME | SS PHARMACEUT CO LTD | 1999-07-21 | — | — | JP | disclosed |
| EP-0913393-A2 | Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it | SSP Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |