Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915402 | 0.81 | KMT2A (0.65) | KMT2AMEN1SIGMAR1POLBMAOB | |
| SCHEMBL13003260 | 0.79 | SIGMAR1 (0.68) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL5789230 | 0.78 | KMT2A (0.59) | KMT2AMEN1SIGMAR1POLBMAOB | |
| SCHEMBL17294676 | 0.77 | CHRM3 (0.72) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL555464 | 0.77 | KMT2A (0.64) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL6952267 | 0.77 | CHRM2 (0.65) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL7144278 | 0.77 | SIGMAR1 (0.61) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL6950046 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL28249789 | 0.76 | DRD4 (0.51) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL3635817 | 0.75 | KMT2A (0.56) | KMT2AMEN1SIGMAR1POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087775-A | Azole derivatives with antimuscarinic activity | CHIESI FARMA SPA (IT) | 2007-12-12 | — | — | CN | disclosed |