Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953811 | 0.94 | CHRM2 (0.54) | SIGMAR1CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6950046 | 0.84 | CHRM2 (0.58) | SIGMAR1DRD4CHRM2CHRM1CHRM3 | |
| SCHEMBL5862230 | 0.74 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9872559 | 0.74 | DRD4 (0.78) | SIGMAR1DRD4MCHR1SMN1; SMN2MEN1 | |
| SCHEMBL7470441 | 0.74 | CHRM2 (0.83) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27502405 | 0.74 | CHRM2 (0.83) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6952267 | 0.73 | CHRM2 (0.65) | SIGMAR1DRD4CHRM2CHRM1CHRM3 | |
| SCHEMBL9727102 | 0.72 | SIGMAR1 (0.72) | SIGMAR1DRD4MCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7475783 | 0.72 | SIGMAR1 (0.65) | SIGMAR1DRD4MCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6550863 | 0.72 | SIGMAR1 (0.60) | SIGMAR1DRD4SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913393-B1 | Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it | SSP CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6060485-A | UROGENITAL DISORDERS | SSP CO., LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| CN-1222510-A | Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it | SSP CO LTD (JP) | 1999-07-14 | — | — | CN | disclosed |
| EP-0913393-A2 | Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it | SSP Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |