Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916660 | 0.90 | SLC7A5 (0.45) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8821951 | 0.83 | GPR119 (0.37) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL3903477 | 0.81 | GABRA1 (0.40) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL6349308 | 0.81 | SLC7A5 (0.43) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL17054121 | 0.81 | NR1H2 (0.37) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL1299593 | 0.81 | CNR1 (0.40) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4040319 | 0.81 | GABRA1 (0.40) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL27621204 | 0.79 | GABRA1 (0.39) | SLC7A5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL128693 | 0.77 | CA1 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL543053 | 0.76 | CA12 (0.49) | SLC7A5GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |