Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950110 | 0.81 | SLC7A5 (0.43) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL422919 | 0.81 | CA1 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6349308 | 0.80 | SLC7A5 (0.43) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL28916660 | 0.79 | SLC7A5 (0.45) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27621204 | 0.78 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3149483 | 0.77 | CA12 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL543053 | 0.74 | CA12 (0.49) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3391247 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL22831626 | 0.74 | CA1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4208340 | 0.74 | CES2 (0.53) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460475-A | 2- (pyridin-2-yl) -pyrimidines as fungicides | BASF SE (DE) | 2009-06-17 | — | — | CN | disclosed |
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | BASF SE (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-2010515-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007116079-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | CBR3, CBR1, CNPY2 | GABRA1 1832/4885GABRG2 2113/4885GABRB3 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.