Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109468 | 0.90 | ALDH1A1 (0.54) | TSHRLMNAPDK1 | |
| SCHEMBL27548058 | 0.89 | CASP6 (0.55) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL27544736 | 0.86 | PDK1 (0.49) | HCAR3LMNAPDK1 | |
| SCHEMBL4175596 | 0.85 | CASP6 (0.58) | CASP6TSHRHCAR3LMNAAPEX1 | |
| SCHEMBL17053413 | 0.85 | PDK1 (0.45) | TSHRHCAR3LMNAPDK1 | |
| SCHEMBL14714240 | 0.84 | KMT2A (0.42) | LMNAPDK1 | |
| SCHEMBL13264670 | 0.83 | CASP6 (0.55) | CASP6TSHRHCAR3LMNAAPEX1 | |
| SCHEMBL6886014 | 0.83 | ALDH1A1 (0.46) | LMNAPDK1 | |
| SCHEMBL19193928 | 0.82 | TSHR (0.50) | TSHRLMNA | |
| SCHEMBL27736701 | 0.82 | CYP1A2 (0.59) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751765-B1 | SULFONAMIDE DERIVATIVES AND THEIR USE | PHARMACOPEIA INC (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0766826-B1 | SYNTHESIS OF COMBINATORIAL LIBRARIES | PHARMACOPEIA INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-5756810-A | Process of preparing 3-nitro benzoate compounds in lower alkanol | PHARMACOPEIA, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0766826-A4 | SYNTHESIS OF COMBINATORIAL LIBRARIES | PHARMACOPEIA INC (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5663046-A | DIRECTLY DIVIDING THE CONTENTS OF EACH SUB-POOL INTO THE SUB-POOLS FOR THE NEXT STEP IN THE SYNTHETIC SCHEME REDUCES THE CALCULABLE ERROR FROM THE THAT OF SPLIT SYNTHESIS | PHARMACOPEIA, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0751765-A4 | SULFONAMIDE DERIVATIVES AND THEIR USE | PHARMACOPEIA INC (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0766826-A1 | SYNTHESIS OF COMBINATORIAL LIBRARIES | PHARMACOPEIA, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| US-5618825-A | ENZYME INHIBITORS; ANTICOAGULANTS; VISION DISORDERS | PHARMACOPEIA, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0751765-A1 | SULFONAMIDE DERIVATIVES AND THEIR USE | PHARMACOPEIA, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995035503-A1 | SYNTHESIS OF COMBINATORIAL LIBRARIES | PHARMACOPEIA, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995024186-A1 | SULFONAMIDE DERIVATIVES AND THEIR USE | PHARMACOPEIA, INC. (US) | 1995-09-14 | — | — | WO | disclosed |