Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950318 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL6950327 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL6955960 | 0.83 | NPC1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL6955964 | 0.83 | NPC1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL6955970 | 0.83 | NPC1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL6960746 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL6960750 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL6960755 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL7717282 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL7717288 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103549-B1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | OREAL (FR) | 2003-06-04 | — | — | EP | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1103549-A1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | L'OREAL (FR) | 2001-05-30 | — | — | EP | claimed |
| EP-1103549-B1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | OREAL (FR) | 2003-06-04 | — | — | EP | disclosed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |