Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | FURIN | P09958 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955970 | 1.00 | NPC1 (0.49) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL6955964 | 1.00 | NPC1 (0.49) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL6950321 | 0.83 | ALDH1A1 (0.56) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL6950318 | 0.83 | ALDH1A1 (0.56) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL6950327 | 0.83 | ALDH1A1 (0.56) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL6960755 | 0.74 | SMN1; SMN2 (0.45) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL6960746 | 0.74 | SMN1; SMN2 (0.45) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL6960750 | 0.74 | SMN1; SMN2 (0.45) | NPC1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL7719406 | 0.74 | NPC1 (0.59) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL7719407 | 0.74 | NPC1 (0.59) | NPC1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103549-B1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | OREAL (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1103549-A1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | L'OREAL (FR) | 2001-05-30 | — | — | EP | disclosed |