Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948735 | 0.84 | NPC1 (0.46) | ALDH1A1ADRA1AKMT2AL3MBTL1MAPT | |
| SCHEMBL6231293 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL6953946 | 0.75 | MAPT (0.41) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL39200 | 0.74 | LMNA (0.55) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL20561123 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL1452206 | 0.74 | TSHR (0.61) | ALDH1A1KMT2AL3MBTL1MAPTUSP2 | |
| SCHEMBL2989810 | 0.74 | ALDH1A1 (0.68) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL13328208 | 0.74 | SMN1; SMN2 (0.58) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL15204568 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL8880799 | 0.74 | ALDH1A1 (0.52) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |