Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096926 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL31347501 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL6947524 | 0.85 | TSHR (0.47) | ALDH1A1HIF1AATMTDP1HTT | |
| SCHEMBL14880650 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL3120356 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL291089 | 0.81 | POLB (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL855601 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL14899811 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL31023151 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1LMNARECQL | |
| SCHEMBL4124874 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230223-B1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA SA (FR) | 2004-02-25 | — | — | EP | disclosed |
| EP-1230223-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | Aventis Pharma S.A. (FR) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032630-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-05-10 | — | — | WO | disclosed |