Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950412 | 0.85 | ALDH1A1 (0.55) | TDP1ATMALDH1A1HIF1AMAPT | |
| SCHEMBL291089 | 0.84 | POLB (0.54) | TSHRMAPK1ALDH1A1HPGDSNCA | |
| SCHEMBL27837847 | 0.84 | MAPT (0.49) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL18138457 | 0.78 | TSHR (0.52) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL10335845 | 0.77 | TSHR (0.43) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL515466 | 0.76 | MAPT (0.54) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL10959235 | 0.76 | TSHR (0.55) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL1117240 | 0.76 | TSHR (0.50) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL6673172 | 0.76 | TSHR (0.50) | TSHRCYP3A4CASP6HTR1ADRD2 | |
| SCHEMBL11695666 | 0.76 | TSHR (0.50) | TSHRCYP3A4CASP6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230223-B1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA SA (FR) | 2004-02-25 | — | — | EP | disclosed |
| EP-1230223-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | Aventis Pharma S.A. (FR) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032630-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-05-10 | — | — | WO | disclosed |