Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679213 | 0.85 | POLB (0.52) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL6947524 | 0.84 | TSHR (0.47) | POLBMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL11002820 | 0.82 | MAPK1 (0.60) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL69585 | 0.82 | SNCA (0.62) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL30477507 | 0.82 | SNCA (0.62) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL6950412 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPSR1CA1 | |
| SCHEMBL1736272 | 0.80 | POLB (0.62) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL1467557 | 0.79 | MAPK1 (0.61) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL1025776 | 0.79 | POLB (0.56) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL3529585 | 0.79 | POLB (0.56) | POLBMAPK1ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759489-B2 | Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-06-24 | — | — | US | claimed |
| US-20120157663-A1 | ANTIBODY IDENTIFYING AN ANTIGEN-BOUND ANTIBODY AND AN ANTIGEN-UNBOUND ANTIBODY, AND METHOD FOR PREPARING THE SAME | Tokyo University Science | 2012-06-21 | — | — | US | claimed |
| US-6503714-B1 | Contacting the sample with a probe under conditions in which said substance if present binds directly or indirectly to the probe, a plurality of nucleobases covalently attached to at least one strand of backbone comprising a plurality of atoms | ROCHE DIAGNOSTICS GMBH (DE) | 2003-01-07 | — | — | US | claimed |
| US-6214549-B1 | CONTACTING SAMPLE WITH PROBE COMPRISING STEM AND BRANCH SUCH THAT SUBSTANCE IF PRESENT BINDS DIRECTLY OR INDIRECTLY TO PROBE; MIXING BINDING PRODUCT WITH CONJUGATE; REMOVING UNBOUND CONJUGATE FROM MIXTURE; DETERMINING PRESENCE OF CONJUGATE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-04-10 | — | — | US | claimed |
| WO-1996029088-A1 | NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-09-26 | — | — | WO | claimed |
| US-12018291-B2 | Compositions and methods for antigen targeting to CD180 | UNIVERSITY OF WASHINGTON (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240197867-A1 | NEURAL CONTROL OF ADAPTIVE IMMUNITY | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2024-06-20 | — | — | US | disclosed |
| WO-2024124052-A1 | IMMUNE ADJUVANTS FOR POLYSACCHARIDE VACCINES | THOMAS JEFFERSON UNIVERSITY (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4380616-A2 | METHOD AND MEANS FOR ENHANCING THERAPEUTIC ANTIBODIES | Vaccinvent GmbH (DE) | 2024-06-12 | — | — | EP | disclosed |
| US-12006364-B2 | Anti-CD100 antibodies and methods for using the same | VACCINEX, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| US-11999772-B2 | Antibodies comprising a polypeptide inserted in framework 3 region | UCB Biopharma SRL (BE) | 2024-06-04 | — | — | US | disclosed |
| US-20240150494-A1 | GLYCOFORM SPECIFIC NANOBODIES AND METHODS OF USE | THE ROCKEFELLER UNIVERSITY | 2024-05-09 | — | — | US | disclosed |
| WO-1986006490-A1 | METHOD FOR AUGMENTING IMMUNE RESPONSE | NEW YORK UNIVERSITY (US) | 1986-11-06 | — | — | WO | disclosed |
| EP-0194276-A1 | PRODUCTION OF CHIMERIC ANTIBODIES. | CELLTECH LTD (GB) | 1986-09-17 | — | — | EP | disclosed |
| WO-1986001533-A1 | PRODUCTION OF CHIMERIC ANTIBODIES | CELLTECH LIMITED (GB) | 1986-03-13 | — | — | WO | disclosed |
| EP-0122080-A1 | A process for the production of a protein | CELLTECH LIMITED (GB) | 1984-10-17 | — | — | EP | disclosed |
| EP-0120694-A2 | Processes for the production of multichain polypeptides or proteins | CELLTECH LIMITED (GB) | 1984-10-03 | — | — | EP | disclosed |
| WO-1984003711-A1 | A PROCESS FOR THE PRODUCTION OF A PROTEIN | CELLTECH LTD (GB) | 1984-09-27 | — | — | WO | disclosed |
| WO-1984003712-A2 | MULTICHAIN POLYPEPTIDES OR PROTEINS AND PROCESSES FOR THEIR PRODUCTION | CELLTECH LTD (GB) | 1984-09-27 | — | — | WO | disclosed |
| EP-0106615-A2 | Assay for the free portion of substances in biological fluids | AMERSHAM INTERNATIONAL plc (GB) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197867-A1 | NEURAL CONTROL OF ADAPTIVE IMMUNITY | TRPV1, TRPA1, TRPV2 | POLB 4841/4885MAPK1 1414/4885ALDH1A1 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.