Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944371 | 0.79 | CHRM2 (0.33) | MEN1KMT2A | |
| SCHEMBL6951975 | 0.79 | CHRM2 (0.33) | MEN1KMT2A | |
| SCHEMBL28237177 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SLC18A3NAAAPRKCA | |
| SCHEMBL6943955 | 0.72 | APLNR (0.39) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6943949 | 0.72 | APLNR (0.39) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL25548059 | 0.69 | ALDH1A1 (0.35) | ALDH1A1SLC18A3NAAAPRKCA | |
| SCHEMBL3944848 | 0.67 | SLC18A3 (0.47) | ALDH1A1SLC18A3NAAAPRKCA | |
| SCHEMBL14271180 | 0.67 | ALDH1A1 (0.45) | ALDH1A1SLC18A3NPSR1MEN1LMNA | |
| SCHEMBL15305155 | 0.66 | CHRM2 (0.41) | LMNA | |
| SCHEMBL8969828 | 0.66 | ALDH1A1 (0.39) | ALDH1A1SLC18A3NPSR1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235832-B1 | VITAMIN D PRESCURSORS, METHOD AND INTERMEDIATES | THERAMEX (MC) | 2003-11-19 | — | — | EP | disclosed |
| EP-1106618-A1 | Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof | LABORATOIRE THERAMEX (MC) | 2001-06-13 | — | — | EP | disclosed |
| US-6191292-B1 | ENZYMATIC ESTERIFICATION OF A DIOL, E.G., METHYL-3-ACETOXY-5-HYDROXY-CYCLOHEXANECARBOXYLATE BY A LIPASE AND VINYL ALKANOATE OR AN ACID ANHYDRIDE; CYCLIZATION TO A BICYCLIC(3.1.0)HEXANE DERIVATIVE | LABORATOIRE THERAMEX (MC) | 2001-02-20 | — | — | US | disclosed |