Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951975 | 1.00 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL12513405 | 0.83 | CHRNB2 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL6950647 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL19101752 | 0.79 | CHRM2 (0.38) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL6950974 | 0.78 | PDE4D (0.31) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL6943949 | 0.78 | APLNR (0.39) | MEN1CYP2D6KMT2ATSHR | |
| SCHEMBL6943955 | 0.78 | APLNR (0.39) | MEN1CYP2D6KMT2ATSHR | |
| SCHEMBL8460680 | 0.78 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL15305138 | 0.76 | GABRR1 (0.38) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL15130720 | 0.74 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235832-B1 | VITAMIN D PRESCURSORS, METHOD AND INTERMEDIATES | THERAMEX (MC) | 2003-11-19 | — | — | EP | disclosed |
| EP-1106618-A1 | Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof | LABORATOIRE THERAMEX (MC) | 2001-06-13 | — | — | EP | disclosed |
| US-6191292-B1 | ENZYMATIC ESTERIFICATION OF A DIOL, E.G., METHYL-3-ACETOXY-5-HYDROXY-CYCLOHEXANECARBOXYLATE BY A LIPASE AND VINYL ALKANOATE OR AN ACID ANHYDRIDE; CYCLIZATION TO A BICYCLIC(3.1.0)HEXANE DERIVATIVE | LABORATOIRE THERAMEX (MC) | 2001-02-20 | — | — | US | disclosed |