Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946765 | 0.92 | CYP2D6 (0.44) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6948071 | 0.92 | RAB9A (0.44) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6948970 | 0.82 | MAPT (0.46) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6946791 | 0.81 | RAB9A (0.54) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6947942 | 0.75 | EGFR (0.43) | MAPTGAA | |
| SCHEMBL6950564 | 0.75 | AAK1 (0.40) | MAPTALDH1A1LMNA | |
| SCHEMBL6944405 | 0.74 | F2 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL6939915 | 0.74 | DHFR (0.56) | MAPTLMNAGAA | |
| SCHEMBL6946589 | 0.73 | MAPT (0.37) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6945088 | 0.73 | CYP1A2 (0.48) | RAB9ANPC1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |