Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595169 | 0.78 | F2 (0.48) | F2F10F7L3MBTL1HRH3 | |
| SCHEMBL6946589 | 0.77 | MAPT (0.37) | HRH3HRH4MAPTKDM4ECYP1A2 | |
| SCHEMBL6945088 | 0.74 | CYP1A2 (0.48) | MAPTMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6950878 | 0.74 | RAB9A (0.53) | ALDH1A1MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL3338581 | 0.73 | F2 (0.61) | F2F10F7CYP1A2CYP2E1 | |
| SCHEMBL6947942 | 0.73 | EGFR (0.43) | MAPTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6948071 | 0.72 | RAB9A (0.44) | ALDH1A1MAPTCYP2D6SMN1; SMN2POLB | |
| SCHEMBL6946765 | 0.72 | CYP2D6 (0.44) | ALDH1A1MAPTCYP2D6MAOBSMN1; SMN2 | |
| SCHEMBL6939915 | 0.72 | DHFR (0.56) | MAPTKDM4EKMT2ACYP1A2CYP3A4 | |
| SCHEMBL6948821 | 0.72 | MAPT (0.40) | L3MBTL1ALDH1A1MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |