Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.38 |
| ▸ | HTR2B | P41595 | 9/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8183831 | 0.99 | HTR2C (0.37) | HTR2CHTR2AHTR2BCHUKPRKD3 | |
| SCHEMBL6954549 | 0.78 | CHRNA7 (0.39) | HTR2CHTR2AHTR2BGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6952537 | 0.73 | BRD4 (0.30) | — | |
| SCHEMBL6950569 | 0.72 | ESR1 (0.35) | HTR2CHTR2AHTR2BADRB2NCF1 | |
| SCHEMBL28112889 | 0.69 | ADRB2 (0.49) | HTR2CHTR2AHTR2BGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6952534 | 0.69 | LMNA (0.42) | NCF1 | |
| SCHEMBL6953391 | 0.69 | KMT2A (0.37) | HTR2A | |
| SCHEMBL7366527 | 0.67 | L3MBTL1 (0.63) | HTR2CHTR2AHTR2BGAAL3MBTL1 | |
| SCHEMBL5461889 | 0.62 | GSK3B (0.52) | HTR2CHTR2AHTR2BPRKD3PRKCG | |
| SCHEMBL38663101 | 0.62 | GSK3B (0.52) | HTR2CHTR2AHTR2BPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669920-B1 | SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-5580982-A | ANTIDEPRESSANTS; ANTICHOLINERGIC AGENTS; ALZHEIMER'S DISEASE; AMINE OXIDASE INHIBITORS | HOECHST MARION ROUSSEL INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5494908-A | ANTIDEPRESSANT | HOECHST-ROUSSEL PHARMACEUTICAL INCORPORATED (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1994012495-A1 | SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-06-09 | — | — | WO | disclosed |