Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946996 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6948585 | 0.86 | RAB9A (0.43) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6944345 | 0.86 | RAB9A (0.43) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6950839 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6946909 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6945466 | 0.80 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6950297 | 0.80 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6950934 | 0.78 | LMNA (0.41) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL6950145 | 0.78 | LMNA (0.41) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7492863 | 0.69 | MTNR1A (0.45) | MTNR1AMTNR1BALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | claimed |