Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 5/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949160 | 0.93 | BRD4 (0.43) | BRD4CREBBPNPC1RAB9AMMP2 | |
| SCHEMBL6953199 | 0.88 | MMP2 (0.45) | BRD4CREBBPNPC1RAB9AMMP2 | |
| Hydrochloric Acid SCHEMBL6953962 | 0.86 | MMP2 (0.47) | BRD4CREBBPNPC1RAB9AMMP2 | |
| SCHEMBL6949858 | 0.84 | CHEK1 (0.41) | BRD4CREBBPNPC1RAB9AMMP2 | |
| SCHEMBL6948954 | 0.79 | NPC1 (0.55) | NPC1RAB9ABRS3PARP1DHODH | |
| SCHEMBL6951916 | 0.77 | DHODH (0.43) | BRD4CREBBPNPC1RAB9ABRS3 | |
| SCHEMBL6953650 | 0.77 | PARP1 (0.44) | BRD4CREBBPNPC1RAB9AMMP2 | |
| SCHEMBL6951750 | 0.77 | BRS3 (0.42) | BRD4CREBBPNPC1RAB9ABRS3 | |
| SCHEMBL6952443 | 0.75 | BRD4 (0.46) | BRD4CREBBPNPC1RAB9AMMP2 | |
| SCHEMBL6943101 | 0.75 | RAB9A (0.50) | BRD4CREBBPNPC1RAB9ARNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |