Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949553 | 0.91 | HTR1A (0.44) | HTR1AHDAC1MAPK1ALDH1A1LMNA | |
| SCHEMBL6947338 | 0.83 | HDAC1 (0.42) | HTR1AHDAC1MAPK1ASAH1MAPT | |
| SCHEMBL6953729 | 0.81 | HTR1A (0.40) | HTR1AHDAC1ALDH1A1LMNAASAH1 | |
| SCHEMBL6952009 | 0.80 | HTR1A (0.42) | HTR1AHDAC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6952640 | 0.78 | HTR1A (0.44) | HTR1AHDAC1MAPK1ALDH1A1LMNA | |
| SCHEMBL6957394 | 0.76 | PPARG (0.44) | HTR1A | |
| SCHEMBL6956944 | 0.74 | HDAC1 (0.41) | HTR1AHDAC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6953855 | 0.71 | HTR1A (0.43) | HTR1AHDAC1MAPK1ALDH1A1LMNA | |
| SCHEMBL6951749 | 0.70 | HTR1A (0.40) | HTR1AHDAC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14565141 | 0.69 | HTR1A (0.67) | HTR1AALDH1A1TSHRHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |