Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952640 | 0.91 | HTR1A (0.44) | HDAC1HTR1AASAH1CAPN1MEN1 | |
| SCHEMBL6952008 | 0.83 | HTR1A (0.41) | HDAC1HTR1AASAH1MAPTMEN1 | |
| SCHEMBL6953729 | 0.81 | HTR1A (0.40) | HDAC1HTR1AASAH1CAPN1MAPT | |
| SCHEMBL6952009 | 0.80 | HTR1A (0.42) | HDAC1HTR1AASAH1MAPTMAPK1 | |
| SCHEMBL6949553 | 0.78 | HTR1A (0.44) | HDAC1HTR1AASAH1MAPTMAPK1 | |
| SCHEMBL6957394 | 0.76 | PPARG (0.44) | HTR1A | |
| SCHEMBL6956944 | 0.74 | HDAC1 (0.41) | HDAC1HTR1AASAH1MAPK1 | |
| SCHEMBL6953855 | 0.71 | HTR1A (0.43) | HDAC1HTR1AASAH1MAPK1 | |
| SCHEMBL6951749 | 0.70 | HTR1A (0.40) | HDAC1HTR1AMAPTMEN1KMT2A | |
| SCHEMBL4672507 | 0.69 | SIGMAR1 (0.53) | HDAC1CNR1CNR2ELANEPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |