SCHEMBL6957394

SCHEMBL6957394

CCCOC(Cc1ccc(CCCn2c(=O)oc3ccccc3c2=O)cc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.44
PPARA Q07869 10/20 0.44
PPARD Q03181 2/20 0.44
PTPN1 P18031 3/20 0.42
HTR1A P08908 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6953729 0.92 HTR1A (0.40) PPARGPPARAPPARDPTPN1HTR1A
SCHEMBL7530015 0.81 PPARG (0.58) PPARGPPARAPPARD
SCHEMBL6949553 0.81 HTR1A (0.44) HTR1A
SCHEMBL6952640 0.81 HTR1A (0.44) HTR1A
SCHEMBL6752687 0.79 PPARA (0.48) PPARGPPARAPPARD
SCHEMBL6947338 0.76 HDAC1 (0.42) HTR1A
SCHEMBL6952008 0.76 HTR1A (0.41) HTR1A
SCHEMBL6952009 0.76 HTR1A (0.42) PPARGPPARAPPARDHTR1A
SCHEMBL6952327 0.76 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL7531569 0.75 PPARG (0.69) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed