Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952092 | 1.00 | MAPT (0.39) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL8009327 | 0.90 | MAPT (0.37) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL6952751 | 0.90 | ALDH1A1 (0.49) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL8009323 | 0.90 | MAPT (0.37) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL6952750 | 0.90 | ALDH1A1 (0.49) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL6947834 | 0.88 | THRB (0.44) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6947838 | 0.88 | THRB (0.44) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6947265 | 0.85 | KAT8 (0.42) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6947262 | 0.85 | KAT8 (0.42) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6953049 | 0.85 | ALDH1A1 (0.39) | MAPTALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743304-B1 | 4-(Arylaminomethylene)-2,4-dihydro-pyrazol-3-ones | MERCK PATENT GMBH (DE) | 2003-03-26 | — | — | EP | claimed |