SCHEMBL6952158

SCHEMBL6952158

OCC(CO)(Cc1ccc(Br)cc1)Cc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.39
HTR2A P28223 1/20 0.39
CYP2A6 P11509 1/20 0.38
IDO1 P14902 4/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
AGER Q15109 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950669 0.80 ACHE (0.40) MEN1KMT2AALDH1A1
SCHEMBL16572213 0.79 TAAR1 (0.38) TAAR1HTR2ACYP2A6IDO1MEN1
SCHEMBL11648 0.77 TAAR1 (0.37) TAAR1HTR2ACYP2A6IDO1MEN1
SCHEMBL15314314 0.76 IDO1 (0.42) TAAR1CYP2A6IDO1MEN1KMT2A
SCHEMBL14935121 0.76 SLC6A4 (0.50) TAAR1HTR2ACYP2A6IDO1MEN1
SCHEMBL2489390 0.75 TSHR (0.50) TAAR1IDO1
SCHEMBL20076110 0.75 CHRM3 (0.46) IDO1
SCHEMBL1737226 0.71 ESR1 (0.43) TAAR1HTR2ACYP2A6IDO1ALOX15
SCHEMBL14935113 0.71 TAAR1 (0.35) TAAR1HTR2ACYP2A6IDO1MEN1
SCHEMBL3269847 0.71 ALDH1A1 (0.48) TAAR1IDO1ALOX15ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10197881-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2019-02-05 US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 US disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 EP disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 EP disclosed
US-9594284-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2017-03-14 US disclosed
US-9594284-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2017-03-14 US disclosed
US-9274395-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2016-03-01 US disclosed
US-9274395-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2016-03-01 US disclosed
US-20150275385-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN USHAS CORP INC (US) 2015-10-01 US disclosed
US-20150275385-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN USHAS CORP INC (US) 2015-10-01 US disclosed
EP-2780762-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE Ashwin-Ushas Corporation, Inc. (US) 2014-09-24 EP disclosed
WO-2013074702-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-23 WO disclosed
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-16 US disclosed
EP-1115729-B1 PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PTP-1B MERCK FROSST CANADA INC (CA) 2003-02-19 EP disclosed
US-6174874-B1 ANTIDIABETIC,-CARCINOGENIC AGENTS; IMPROVING GLUCOSE TOLERANCE/INSULIN-SENSITIVITY; PREVENTING/TREATING OBESITY AND NEURODEGENERATIVE DISEASES; E.G. 1,3-BIS-((PHOSPHONODI-FLUOROMETHYL)PHENYL)-2-DICARBOXYPROPANE MERCK FROSST CANADA & CO. (CA) 2001-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10197881-B2 Complimentary polymer electrochromic device PMS2, PARG, EED TAAR1 3131/4885HTR2A 1863/4885CYP2A6 3894/4885
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE PMS2, PARG, EED TAAR1 3131/4885HTR2A 1863/4885CYP2A6 3894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.