Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 18/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951920 | 0.91 | HTR4 (0.55) | HTR4KCNH2KDM4EGAAHSD17B10 | |
| SCHEMBL7391976 | 0.90 | HTR4 (0.66) | HTR4KCNH2HTR2A | |
| SCHEMBL6949375 | 0.90 | HTR4 (0.52) | HTR4KCNH2KDM4EHSD17B10HTR2A | |
| SCHEMBL6944917 | 0.88 | HTR4 (0.51) | HTR4KCNH2HTR2AMEN1KMT2A | |
| SCHEMBL6952232 | 0.86 | HTR4 (0.59) | HTR4KCNH2KDM4EHTR2A | |
| SCHEMBL6950902 | 0.83 | HSD17B10 (0.51) | HTR4KCNH2KDM4EGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL6952970 | 0.82 | KDM4E (0.53) | HTR4KCNH2KDM4EGAAHSD17B10 | |
| SCHEMBL6953804 | 0.81 | CNR1 (0.56) | HTR4KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL6957277 | 0.80 | HTR4 (0.53) | HTR4KCNH2KDM4EHSD17B10HTR2A | |
| Hydrochloric Acid SCHEMBL7393717 | 0.79 | HTR4 (0.65) | HTR4KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |