SCHEMBL69530

SCHEMBL69530

O=C(Oc1ccccc1)c1ccnc(C(=O)Oc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.60
ALDH1A1 P00352 5/20 0.60
NSD2 O96028 1/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
HSD17B10 Q99714 2/20 0.49
KDM6B O15054 1/20 0.49
TET3 O43151 1/20 0.49
KDM4A O75164 1/20 0.49
BBOX1 O75936 1/20 0.49
KDM5A P29375 1/20 0.49
KDM5C P41229 1/20 0.49
ASPH Q12797 1/20 0.49
KDM4D Q6B0I6 1/20 0.49
TET2 Q6N021 1/20 0.49
ALKBH5 Q6P6C2 1/20 0.49
KDM7A Q6ZMT4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28033804 0.87 MAPT (0.60) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL5700035 0.82 MAPT (0.48) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL27466786 0.82 MAPT (0.63) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL5700542 0.82 ALDH1A1 (0.59) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL5700381 0.82 MAPT (0.48) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL4537268 0.82 ALDH1A1 (0.59) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL28196130 0.81 MAPT (0.47) MAPTALDH1A1NSD2KMT2AMEN1
SCHEMBL8939375 0.79 MAPT (0.58) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL30185288 0.79 MAPT (0.69) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL3961211 0.79 MAPT (0.69) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885ALDH1A1 1882/4885NSD2 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.