Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69530 | 0.87 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL29466587 | 0.85 | JMJD6 (0.57) | SMN1; SMN2KMT2ALMNAGABRPGABRD | |
| SCHEMBL930636 | 0.85 | JMJD6 (0.57) | SMN1; SMN2KMT2ALMNAGABRPGABRD | |
| SCHEMBL1920448 | 0.83 | FTO (0.61) | MAPTALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL23327392 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL29930605 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL16578099 | 0.80 | KDM4E (0.61) | MAPTSMN1; SMN2ALDH1A1KMT2AJMJD6 | |
| SCHEMBL9297593 | 0.80 | CYP1A2 (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL8126380 | 0.79 | CYP1A2 (0.51) | MAPTSMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL8950955 | 0.79 | MMP2 (0.48) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981458-A | Inhibitors of histone demethylases | EPITHERAPEUTICS APS | 2015-10-14 | — | — | CN | disclosed |