Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953028 | 1.00 | HDAC1 (0.49) | HDAC1RAB9ANPC1HDAC6HDAC3 | |
| SCHEMBL6951815 | 0.85 | ALOX5 (0.45) | HDAC1RAB9ANPC1HDAC6HDAC3 | |
| SCHEMBL6952013 | 0.83 | RAB9A (0.55) | HDAC1RAB9ANPC1HDAC6HDAC3 | |
| SCHEMBL6953034 | 0.80 | HDAC1 (0.49) | HDAC1RAB9ANPC1HDAC6HDAC3 | |
| SCHEMBL6948954 | 0.78 | NPC1 (0.55) | RAB9ANPC1HDAC6RNASEH1 | |
| SCHEMBL29412049 | 0.75 | PARP1 (0.60) | RAB9ANPC1 | |
| SCHEMBL6945364 | 0.75 | RAB9A (0.52) | RAB9ANPC1HDAC6ALDH1A1MAPT | |
| Maleic Acid SCHEMBL6948865 | 0.75 | RAB9A (0.41) | HDAC1RAB9ANPC1HDAC6HDAC3 | |
| SCHEMBL6946391 | 0.74 | CHRM1 (0.55) | RAB9ANPC1HDAC6ALDH1A1MAPT | |
| SCHEMBL6953982 | 0.74 | RAB9A (0.58) | RAB9ANPC1HDAC6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |