Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.63 |
| ▸ | MMP1 | P03956 | 8/20 | 0.63 |
| ▸ | MMP9 | P14780 | 7/20 | 0.57 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956557 | 0.90 | MMP9 (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL6953525 | 0.88 | MME (0.57) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL7384525 | 0.87 | MME (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL8387108 | 0.87 | MME (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL6415164 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL7427129 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL7384875 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL7898741 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL7479163 | 0.85 | MME (0.57) | MMP3MMP1MMP9MMP2MME | |
| SCHEMBL6951780 | 0.84 | MMP3 (0.46) | MMP3MMP1MMP9MMP2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824544-B1 | PEPTIDYL COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-04-16 | — | — | EP | claimed |