Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 16/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954029 | 1.00 | CASP1 (0.44) | CASP1 | |
| SCHEMBL4030680 | 0.89 | TACR1 (0.48) | CASP1 | |
| SCHEMBL4023426 | 0.89 | CASP1 (0.42) | CASP1 | |
| SCHEMBL4023417 | 0.89 | CASP1 (0.42) | CASP1 | |
| SCHEMBL4030676 | 0.89 | TACR1 (0.48) | CASP1 | |
| Dicyclohexylcarbodiimide SCHEMBL7331275 | 0.89 | CASP1 (0.41) | CASP1 | |
| SCHEMBL4021273 | 0.88 | CTSK (0.46) | CASP1 | |
| SCHEMBL4022451 | 0.86 | ATM (0.43) | CASP1 | |
| SCHEMBL4022449 | 0.86 | ATM (0.43) | CASP1 | |
| SCHEMBL6954036 | 0.83 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738150-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6117866-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |