Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964824 | 0.84 | ALDH1A1 (0.51) | MAOBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL22410705 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL6965350 | 0.83 | GAA (0.44) | MAOBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL13017491 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6786224 | 0.75 | POLB (0.57) | MAOBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6965347 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL15826018 | 0.75 | ALDH1A1 (0.49) | MAOBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28193476 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6963709 | 0.74 | KMT2A (0.48) | MAOBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL20448882 | 0.74 | ALDH1A1 (0.51) | MAOBALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247692-B1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LTD (IN) | 2022-09-07 | — | — | EP | disclosed |
| US-10336723-B2 | Inhibitors of TrkA kinase | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2019-07-02 | — | — | US | disclosed |
| US-20180009781-A1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2018-01-11 | — | — | US | disclosed |
| EP-3247692-A1 | INHIBITORS OF TRKA KINASE | GVK Biosciences Private Limited (IN) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016116900-A1 | INHIBITORS OF TRKA KINASE | GVK BIOSCIENCES PRIVATE LIMITED (IN) | 2016-07-28 | — | — | WO | disclosed |
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009781-A1 | INHIBITORS OF TRKA KINASE | NGFR, NGF, NTRK1 | MAOB 2030/4885ALDH1A1 2186/4885KDM4E 2967/4885 |
| US-10336723-B2 | Inhibitors of TrkA kinase | NGFR, EDNRA, NGF | MAOB 1481/4885ALDH1A1 2317/4885KDM4E 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.