Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956345 | 0.84 | GPR119 (0.42) | USP30DPP4ALDH1A1CASP1RIPK1 | |
| SCHEMBL6954026 | 0.81 | SLC18A3 (0.51) | SLC18A3 | |
| SCHEMBL6042688 | 0.80 | USP30 (0.43) | USP30SLC6A9HSD11B1KDM5ASIGMAR1 | |
| SCHEMBL6952881 | 0.73 | MEN1 (0.42) | L3MBTL1ALDH1A1SLC18A3 | |
| SCHEMBL6947646 | 0.73 | MEN1 (0.42) | L3MBTL1ALDH1A1SLC18A3 | |
| SCHEMBL6951299 | 0.73 | NPC1 (0.50) | L3MBTL1ALDH1A1 | |
| SCHEMBL6953373 | 0.73 | MEN1 (0.41) | SLC18A3 | |
| SCHEMBL6954969 | 0.72 | CHRNB2 (0.43) | — | |
| SCHEMBL6959529 | 0.72 | KMT2A (0.40) | CYP3A4CYP2C9L3MBTL1ALDH1A1CYP2D6 | |
| SCHEMBL6952186 | 0.72 | SLC6A3 (0.40) | SIGMAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |