Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 16/20 | 0.56 |
| ▸ | PPARD | Q03181 | 5/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955348 | 0.84 | MAPK1 (0.63) | PPARGPPARAPPARDRAB9A | |
| SCHEMBL6957273 | 0.80 | PPARG (0.47) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6956263 | 0.80 | PPARG (0.45) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6949013 | 0.80 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6957154 | 0.80 | TNF (0.49) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6952622 | 0.79 | TNF (0.44) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6949208 | 0.78 | PPARA (0.56) | PPARGPPARAPPARDRAB9A | |
| SCHEMBL6952971 | 0.78 | SMN1; SMN2 (0.65) | PPARGPPARAPPARDRAB9A | |
| SCHEMBL6556018 | 0.77 | MAPK1 (0.59) | PPARGPPARAPPARDRAB9A | |
| SCHEMBL6950862 | 0.77 | TNF (0.55) | PPARGPPARAPPARDTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |